Speaker
Prof.
Michael Rappolt
(School of Food Science and Nutrition, University of Leeds)
Description
After an introduction into global scattering analysis methods for bilayer membrane systems and after some remarks on how one can exploit even poor diffraction data, recent studies on the interaction of flavonoids with different model membranes systems are presented. Flavonoids are of great importance concerning the health benefits of foods and food additives due to their potential anti-oxidative, anti-inflammatory and immune regulatory actions. It is eminent that flavonoid consumption reduces the risk of several chronic diseases, including cancer and diabetes. Interactions of flavonoids with lipids, via their adsorption at the membrane water interface or insertion into the lipid chain region, can alter the lipid bilayers features (e.g. thickness, fluctuations and fluidity), and thus, influence their therapeutic potentials. The overall aim is to understand the structure-function relationship of flavonoids in the biomembrane in order to design functional food with an higher bioavailability profile.
| Topic Area / Session | Lipids |
|---|
Primary author
Prof.
Michael Rappolt
(School of Food Science and Nutrition, University of Leeds)
